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Does FZ client have trouble playing nice with another program that's running if it also has FTP capability in it?
FileZilla doesn't interfere with third-party programs.
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I have Directory Opus installed, great file manager by the way, and it has FTP in it as well. I have noticed that if I kill DO and then try FZ most of the time it will open and function. But there are still times it hangs.
How deeply does that program nest in the system? After all it is advertised as Explorer replacement. Replacing Explorer is no small task as it's a core system component.